Serum sclerostin in rheumatoid-induced osteoporosis
نویسندگان
چکیده
منابع مشابه
Serum sclerostin levels in men with idiopathic osteoporosis.
OBJECTIVE Sclerostin inhibits osteoblast differentiation and bone formation. If aberrant sclerostin action is involved in less efficient bone acquisition in men with idiopathic low bone mass, this might be reflected in higher serum sclerostin levels. METHODS In 116 men with idiopathic osteoporosis (≤65 years old), 40 of their sons and healthy controls, areal bone parameters were measured usin...
متن کاملSclerostin inhibition for osteoporosis--a new approach.
1. Cunningham SA, Kramer MR, Narayan KMV. Incidence of childhood obesity in the United States. N Engl J Med 2014;370: 403-11. 2. Taveras EM, Rifas-Shiman SL, Sherry B, et al. Crossing growth percentiles in infancy and risk of obesity in childhood. Arch Pediatr Adolesc Med 2011;165:993-8. 3. Van Cleave J, Gortmaker SL, Perrin JM. Dynamics of obesity and chronic health conditions among children a...
متن کاملOsteoporosis in rheumatoid arthritis.
OBJECTIVE To answer and comment on a number of controversial issues in relation to osteoporosis and rheumatoid arthritis (RA), including: Is osteoporosis an extra-articular manifestation of rheumatoid arthritis? Does periarticular osteoporosis reflect disease activity in early arthritis? Is there a threshold for corticosteroid-induced osteoporosis? Can anti-resorbing drugs prevent rheumatoid ar...
متن کاملAnti-sclerostin antibodies and the future treatment of osteoporosis
Osteoporosis is a bone disorder characterized by the reduction of bone mass and/or volume in a normally mineralized bone. This ultimately results in reduction in the mechanical strength of bone making it more vulnerable to minimal trauma fracture [1]. Osteoporosis is highly prevalent in elderly especially postmenopausal women and it can increase both morbidity and mortality. It is estimated tha...
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ژورنال
عنوان ژورنال: Egyptian Rheumatology and Rehabilitation
سال: 2020
ISSN: 2090-3235
DOI: 10.1186/s43166-020-00015-4